diff --git a/llgo/cmd/gllgo/gllgo.go b/llgo/cmd/gllgo/gllgo.go
index 9147e393e75..cef90c074c5 100644
--- a/llgo/cmd/gllgo/gllgo.go
+++ b/llgo/cmd/gllgo/gllgo.go
@@ -117,7 +117,7 @@ func (san *sanitizerOptions) addPasses(mpm, fpm llvm.PassManager) {
 	case san.thread:
 		mpm.AddThreadSanitizerPass()
 	case san.memory:
-		mpm.AddMemorySanitizerPass()
+		mpm.AddMemorySanitizerLegacyPassPass()
 	case san.dataflow:
 		blacklist := san.blacklist
 		if blacklist == "" {
diff --git a/llgo/irgen/runtime.go b/llgo/irgen/runtime.go
index 485a2d3eb0e..3731ff1880c 100644
--- a/llgo/irgen/runtime.go
+++ b/llgo/irgen/runtime.go
@@ -517,7 +517,6 @@ func newRuntimeInterface(module llvm.Module, tm *llvmTypeMap) (*runtimeInterface
 			llvm.PointerType(llvm.Int8Type(), 0),
 			llvm.Int8Type(),
 			tm.target.IntPtrType(),
-			llvm.Int32Type(),
 			llvm.Int1Type(),
 		},
 		false,
@@ -530,8 +529,7 @@ func newRuntimeInterface(module llvm.Module, tm *llvmTypeMap) (*runtimeInterface
 		[]llvm.Type{
 			llvm.PointerType(llvm.Int8Type(), 0),
 			llvm.PointerType(llvm.Int8Type(), 0),
-			tm.target.IntPtrType(),
-			llvm.Int32Type(),
+			llvm.Int64Type(),
 			llvm.Int1Type(),
 		},
 		false,
@@ -589,9 +587,8 @@ func (fr *frame) memsetZero(ptr llvm.Value, size llvm.Value) {
 	ptr = fr.builder.CreateBitCast(ptr, llvm.PointerType(llvm.Int8Type(), 0), "")
 	fill := llvm.ConstNull(llvm.Int8Type())
 	size = fr.createZExtOrTrunc(size, fr.target.IntPtrType(), "")
-	align := llvm.ConstInt(llvm.Int32Type(), 1, false)
 	isvolatile := llvm.ConstNull(llvm.Int1Type())
-	fr.builder.CreateCall(memset, []llvm.Value{ptr, fill, size, align, isvolatile}, "")
+	fr.builder.CreateCall(memset, []llvm.Value{ptr, fill, size, isvolatile}, "")
 }
 
 func (fr *frame) memcpy(dest llvm.Value, src llvm.Value, size llvm.Value) {
@@ -599,9 +596,8 @@ func (fr *frame) memcpy(dest llvm.Value, src llvm.Value, size llvm.Value) {
 	dest = fr.builder.CreateBitCast(dest, llvm.PointerType(llvm.Int8Type(), 0), "")
 	src = fr.builder.CreateBitCast(src, llvm.PointerType(llvm.Int8Type(), 0), "")
 	size = fr.createZExtOrTrunc(size, fr.target.IntPtrType(), "")
-	align := llvm.ConstInt(llvm.Int32Type(), 1, false)
 	isvolatile := llvm.ConstNull(llvm.Int1Type())
-	fr.builder.CreateCall(memcpy, []llvm.Value{dest, src, size, align, isvolatile}, "")
+	fr.builder.CreateCall(memcpy, []llvm.Value{dest, src, size, isvolatile}, "")
 }
 
 func (fr *frame) returnAddress(level uint64) llvm.Value {